@font-face{font-family:Manrope;src:url('../fonts/manrope-variable.woff2') format('woff2');font-weight:200 800;font-style:normal;font-display:swap}

:root{
  --ink:#101b49;
  --ink-soft:#425078;
  --purple-deep:#783394;
  --lilac:#f3e7f8;
  --orange:#f28b18;
  --teal:#0f8b8d;
  --teal-deep:#0b6668;
  --amber:#d97a1f;
  --red:#b8452b;
  --clinical-50:#f4f7f8;
  --paper:#fff;
  --mist:#f6f8fb;
  --slate:#eef1f6;
  --line:rgba(16,27,73,.12);
  --shadow:0 20px 50px rgba(16,27,73,.10);
}

*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{margin:0;background:var(--paper);color:var(--ink);font-family:Manrope,system-ui,sans-serif;line-height:1.62;-webkit-font-smoothing:antialiased;overflow-x:hidden}
img,svg{display:block;max-width:100%;height:auto}
a{color:inherit}
p{margin:0 0 1.15rem}
ul{margin:0}
table{max-width:100%}
.skip-link{position:fixed;z-index:99;top:1rem;left:1rem;padding:.75rem 1rem;background:var(--ink);color:#fff;transform:translateY(-160%);border-radius:.6rem;text-decoration:none}
.skip-link:focus{transform:none}

/* Header */
.site-header{min-height:76px;display:flex;flex-wrap:wrap;align-items:center;justify-content:space-between;gap:.6rem;padding:1rem clamp(1.2rem,4vw,5rem);position:relative;z-index:5;width:100%;color:var(--ink);background:#fff;border-bottom:1px solid var(--line)}
.brand{display:inline-flex;align-items:center;text-decoration:none}
.brand-logo{display:block;width:clamp(132px,15vw,164px);height:auto}
.header-link{font-size:.78rem;text-decoration:none;text-transform:uppercase;letter-spacing:.1em;font-weight:750;border-bottom:1px solid currentColor;padding-bottom:.15rem}
.button:focus-visible,.header-link:focus-visible,.brand:focus-visible{outline:3px solid var(--orange);outline-offset:4px}
a:focus-visible,summary:focus-visible{outline:3px solid var(--orange);outline-offset:3px}

/* Buttons */
.button{display:inline-flex;align-items:center;justify-content:center;min-height:52px;padding:.8rem 1.5rem;border-radius:.7rem;background:var(--ink);color:#fff;text-decoration:none;font-weight:750;box-shadow:0 10px 24px rgba(16,27,73,.16);transition:transform .2s,box-shadow .2s;border:1px solid transparent;font-size:.95rem}
.button:hover{transform:translateY(-2px);box-shadow:0 14px 30px rgba(16,27,73,.22)}
.button-outline{background:transparent;color:var(--ink);border:1.5px solid var(--ink);box-shadow:none}
.button-outline:hover{background:var(--ink);color:#fff}
.button-teal{background:var(--teal);box-shadow:0 10px 24px rgba(15,139,141,.28)}
.button-teal:hover{background:var(--teal-deep)}
.button-sm{min-height:44px;padding:.6rem 1.1rem;font-size:.85rem}

/* Layout helpers */
.section{padding:clamp(3rem,8vw,6.5rem) clamp(1.2rem,5vw,6rem)}
.section-heading{max-width:760px;margin-bottom:2.2rem}
.eyebrow{margin-bottom:.9rem;color:var(--teal-deep);font-size:.72rem;font-weight:800;text-transform:uppercase;letter-spacing:.16em}
h1,h2,h3{letter-spacing:-.03em;margin:0 0 1rem}
.section-heading h2{font-size:clamp(1.7rem,3.6vw,2.5rem);line-height:1.1;margin-bottom:1rem}
.section-heading p{color:var(--ink-soft);font-size:1.02rem}
h3{font-size:1.15rem;margin:1.8rem 0 .8rem}
.fine-print{font-size:.78rem;color:#6b7593}
.max-prose{max-width:760px}

/* Intro / H1 — sobrio, clínico: sin gradiente de color como reclamo */
.guide-intro{position:relative;padding:clamp(3.2rem,9vw,5.5rem) clamp(1.2rem,5vw,6rem) clamp(2.4rem,6vw,3.5rem);background:linear-gradient(160deg,#fff 55%,var(--clinical-50))}
.guide-intro:before{content:"";position:absolute;top:0;left:0;right:0;height:4px;background:var(--teal-deep)}
.guide-intro h1{font-size:clamp(1.8rem,4.6vw,2.7rem);line-height:1.15;letter-spacing:-.03em;max-width:22ch;margin:0 0 1.2rem}
.guide-lead{font-size:1.08rem;color:var(--ink-soft);max-width:62ch}
.guide-lead + .guide-lead{margin-top:-.3rem}

/* En 30 segundos */
.thirty{background:#fff;border:1px solid var(--line);border-left:5px solid var(--teal);border-radius:1rem;padding:1.5rem 1.7rem;box-shadow:var(--shadow);max-width:760px;margin-top:2rem}
.thirty h2{font-size:1rem;text-transform:uppercase;letter-spacing:.1em;color:var(--teal-deep);margin-bottom:1rem}
.thirty ul{list-style:none;padding:0;margin:0;display:grid;gap:.75rem}
.thirty li{display:flex;gap:.75rem;align-items:flex-start;font-size:.98rem;color:var(--ink)}
.thirty li:before{content:"";flex:none;width:9px;height:9px;border-radius:50%;background:var(--teal-deep);margin-top:.5rem}

/* Evidence-level tags */
.eg-tag{display:inline-block;font-size:.68rem;font-weight:800;text-transform:uppercase;letter-spacing:.07em;padding:.3rem .65rem;border-radius:999px;margin:0 0 .8rem}
.eg-tag--experimento{background:#e4f3f2;color:var(--teal-deep)}
.eg-tag--serie{background:var(--lilac);color:var(--purple-deep)}
.eg-tag--revision{background:#eef1f6;color:var(--ink-soft)}
.eg-tag--limitada{background:#fdf1e4;color:#a1490f}
.eg-legend{list-style:none;padding:0;margin:0 0 2rem;display:flex;flex-wrap:wrap;gap:.6rem .9rem;max-width:760px}
.eg-legend li{display:flex;align-items:center;gap:.5rem;font-size:.82rem;color:var(--ink-soft)}

/* Callouts genéricos */
.callout-box{border-radius:1rem;padding:1.4rem 1.6rem;margin:1.6rem 0;max-width:760px}
.callout-box p{margin:0}
.callout-box.info{background:var(--mist);border:1px solid var(--line);border-left:4px solid var(--teal)}
.callout-box.warning{background:#fff;border:1px solid rgba(184,69,43,.3);border-left:4px solid var(--red)}
.strong-line{font-weight:800;font-size:1.02rem;color:var(--ink);border-left:3px solid var(--red);padding-left:1rem;margin:1.2rem 0;max-width:760px}

/* Seguridad / conducción: bloque visible, no alarmista */
.safety{background:var(--ink);color:#fff}
.safety .eyebrow{color:#f0c68a}
.safety .section-heading h2{color:#fff}
.safety-conclusion{background:rgba(255,255,255,.08);border:1px solid rgba(255,255,255,.2);border-left:5px solid var(--red);border-radius:1rem;padding:1.6rem 1.8rem;font-size:1.05rem;font-weight:700;line-height:1.45;max-width:780px;margin:0 0 1.4rem}
.safety p{color:#d7dcf0;max-width:780px}
.safety .fine-print{color:#aab1cf}
.safety-list{list-style:none;padding:0;margin:0 0 1.4rem;display:grid;gap:.7rem;max-width:780px}
.safety-list li{display:flex;gap:.7rem;align-items:flex-start;font-size:.95rem;color:#d7dcf0}
.safety-list li:before{content:"";flex:none;width:8px;height:8px;border-radius:50%;background:#f0c68a;margin-top:.55rem}
.safety-550{background:rgba(184,69,43,.22);border:1px solid rgba(184,69,43,.5);border-radius:1rem;padding:1.3rem 1.5rem;max-width:780px}
.safety-550 strong{color:#fff}

/* Escala de niveles (chips discretos, no gradiente decorativo a pantalla completa) */
.level-scale{display:flex;flex-wrap:wrap;gap:.6rem;margin:1.4rem 0 1.6rem;max-width:780px}
.level-chip{display:flex;align-items:center;gap:.5rem;padding:.5rem .9rem;border:1px solid var(--line);border-radius:999px;background:#fff;font-size:.82rem;color:var(--ink-soft)}
.level-chip__swatch{width:14px;height:14px;border-radius:50%;flex:none;border:1px solid rgba(16,27,73,.15)}
.level-chip--450 .level-chip__swatch{background:#e8c15a}
.level-chip--511 .level-chip__swatch{background:#dd9a3c}
.level-chip--527 .level-chip__swatch{background:#c66f2e}
.level-chip--550 .level-chip__swatch{background:#9c3f27}

/* Proceso de selección clínica (necesidad → tarea → prueba → respuesta → tolerancia) */
.process-chain{display:grid;gap:.9rem;margin:1.8rem 0 1.2rem;max-width:960px}
.process-chain__step{display:flex;gap:1rem;align-items:flex-start;padding:1rem 1.2rem;border:1px solid var(--line);border-radius:.9rem;background:#fff}
.process-chain__num{flex:none;width:28px;height:28px;border-radius:50%;background:var(--ink);color:#fff;display:flex;align-items:center;justify-content:center;font-weight:800;font-size:.85rem}
.process-chain__body strong{display:block;font-size:.96rem;margin-bottom:.15rem}
.process-chain__body span{font-size:.85rem;color:var(--ink-soft)}
.process-chain__arrow{text-align:center;color:var(--ink-soft);font-size:.85rem;margin:-.4rem 0}
@media (min-width:820px){
  .process-chain{grid-auto-flow:column;grid-auto-columns:1fr}
  .process-chain__step{flex-direction:column;text-align:left}
  .process-chain__arrow{writing-mode:horizontal-tb;align-self:center;margin:0;padding:0 .2rem}
}

/* Comparativa "qué sabemos / qué no sabemos" y tabla de estudios: tabla en escritorio, tarjetas en móvil */
.compare-table,.studies-table{display:grid;gap:.7rem;margin-top:1.2rem;max-width:100%}
.compare-row,.studies-row{display:grid;grid-template-columns:1fr;gap:.5rem;padding:1.1rem 1.2rem;border:1px solid var(--line);border-radius:.9rem;background:#fff}
.compare-row span[role="cell"],.studies-row span[role="cell"]{font-size:.88rem;color:var(--ink-soft);line-height:1.55}
.compare-row span[role="cell"]:before,.studies-row span[role="cell"]:before{content:attr(data-label) ": ";font-weight:800;color:var(--ink);display:block;font-size:.72rem;text-transform:uppercase;letter-spacing:.05em;margin-bottom:.15rem}
.compare-head,.studies-head{display:none}
@media (min-width:860px){
  .compare-table,.studies-table{gap:0;border:1px solid var(--line);border-radius:.9rem;overflow:hidden;background:#fff}
  .compare-row{grid-template-columns:1fr 1fr}
  .studies-row{grid-template-columns:1.15fr 1.05fr .95fr 2fr 1.25fr}
  .compare-row,.studies-row{gap:1.1rem;align-items:start;border:none;border-bottom:1px solid var(--line);border-radius:0;padding:1rem 1.2rem}
  .compare-row:last-child,.studies-row:last-child{border-bottom:none}
  .compare-head,.studies-head{display:grid;background:var(--mist);font-weight:800;font-size:.68rem;text-transform:uppercase;letter-spacing:.06em;color:var(--ink)}
  .compare-row span[role="cell"]:before,.studies-row span[role="cell"]:before{content:none}
  .compare-row span[role="cell"],.studies-row span[role="cell"]{font-size:.84rem}
}
.studies-details{margin-top:1.3rem;max-width:100%}
.studies-details summary,.faq-item summary{list-style:none;cursor:pointer}
.studies-details summary::-webkit-details-marker,.faq-item summary::-webkit-details-marker{display:none}
.studies-details summary .button{pointer-events:none}

/* FAQ como acordeón accesible (details/summary nativo) */
.faq-list{display:grid;gap:.8rem;max-width:820px}
.faq-item{border:1px solid var(--line);border-radius:.9rem;background:#fff;padding:.3rem 1.2rem}
.faq-item summary{padding:1rem 0;font-weight:750;font-size:1rem;display:flex;justify-content:space-between;align-items:center;gap:1rem}
.faq-item summary:after{content:"+";flex:none;font-size:1.3rem;color:var(--teal-deep);transition:transform .2s}
.faq-item[open] summary:after{transform:rotate(45deg)}
.faq-item p{color:var(--ink-soft);padding-bottom:1.1rem;margin:0}

/* Bloque relacionado (sin precios, sin promesa de sueño ni beneficio circadiano) */
.related{background:var(--slate)}
.related-cards{display:grid;gap:1rem;max-width:900px}
.related-card{background:#fff;border:1px solid var(--line);border-radius:1rem;padding:1.6rem 1.8rem;display:flex;flex-wrap:wrap;gap:1.2rem;align-items:center;justify-content:space-between}
.related-card p{margin:0;color:var(--ink-soft);max-width:46ch}

/* Fuentes / bibliografía */
.sources{background:#fff}
.sources-updated{display:inline-block;font-size:.78rem;font-weight:750;color:var(--teal-deep);background:var(--lilac);border-radius:999px;padding:.4rem .9rem;margin-bottom:1.6rem}
.sources-list{list-style:none;padding:0;margin:0;display:grid;gap:1rem;max-width:820px}
.sources-list li{border:1px solid var(--line);border-radius:.9rem;padding:1.1rem 1.3rem;display:flex;flex-direction:column;gap:.2rem;scroll-margin-top:1.5rem}
.sources-list .src-num{color:var(--teal-deep);font-weight:800;font-size:.8rem}
.sources-list .src-title{font-weight:750}
.sources-list .src-org{font-size:.82rem;color:var(--ink-soft)}
.sources-list a{color:var(--purple-deep);font-size:.85rem;text-decoration:underline;text-underline-offset:.2rem;word-break:break-word}
.sources-list li:target{outline:2px solid var(--teal);outline-offset:4px;background:var(--mist)}
.sources-note{max-width:760px;color:var(--ink-soft);font-size:.9rem;margin-top:1.8rem}

/* Citas en línea → enlazan a #fuentes */
sup a.cite{color:var(--purple-deep);text-decoration:none;font-weight:700}
sup a.cite:hover,sup a.cite:focus-visible{text-decoration:underline}
.safety sup a.cite{color:#f0c68a}

/* Footer */
.site-footer{padding:3rem 1.2rem;text-align:center;background:#0b1439;color:#fff;display:flex;flex-direction:column;align-items:center;gap:.7rem}
.brand-footer{font-size:1.3rem}
.brand-logo-footer{width:178px;background:#fff;border-radius:.45rem;padding:.25rem}
.site-footer p{margin:0;color:#cbd0e0;font-size:.78rem}
.site-footer .copyright{color:#858da8}
.legal-links{display:flex;flex-wrap:wrap;justify-content:center;gap:.45rem 1rem}
.legal-links a{color:#cbd0e0;font-size:.7rem;text-underline-offset:.2rem}
.legal-links a:hover{color:#fff}

/* Reveal-on-scroll */
.reveal{opacity:1;transform:none}
.js .reveal{opacity:0;transform:translateY(16px);transition:opacity .6s ease,transform .6s ease}
.js .reveal.is-visible{opacity:1;transform:none}

/* Responsive */
@media (min-width:700px){
  .site-footer{flex-direction:row;justify-content:space-between;padding-inline:5vw;flex-wrap:wrap}
  .site-footer .copyright{margin-left:auto}
  .legal-links{order:4;flex-basis:100%}
  .related-cards{grid-template-columns:1fr 1fr}
}
@media (max-width:420px){
  .site-header{padding:.9rem 1.2rem}
  .header-link{font-size:.64rem}
  .related-card{flex-direction:column;align-items:flex-start}
}
@media (prefers-reduced-motion:reduce){
  html{scroll-behavior:auto}
  .js .reveal{opacity:1;transform:none;transition:none}
  .button{transition:none}
  .faq-item summary:after{transition:none}
}